Studies have demonstrated symptoms of at least mild depression in up to a third of patients with smell dysfunction. Interestingly, the reverse is also true: patients with depression often have impaired olfactory function. As might be expected, depression also appears to influence how much people like or dislike smells, whereby unpleasant odours are perceived as more unpleasant, and pleasant odours as less pleasant (ie, an overall negative shift in ‘hedonic’ perception). These changes could be due to altered neuronal processing of odour signals, which has been demonstrated using olfactory electroencephalography, in patients with depression and in healthy participants who’d watched a sad movie .
rhyme or reason Sense, justification, explanation, cause, motivation; reasonableness, reason. The rhyme of the phrase remains as a superfluous alliterative element, providing added emphasis. Apparently it originally referred to amusement or entertainment, since works written in verse were considered aimed toward those ends; the reason of the phrase meant instruction or enlightenment, the supposed province of prose. Today the words usually appear in negative structures or contexts denoting their absence: without rhyme or reason, neither rhyme nor reason, what possible rhyme or reason? The expression was used in this sense of ‘reasonableness’ only as early as 1664 by Henry More: